In Kid Icarus: Uprising for the Nintendo 3DS, you can find twelve Zodiac Chambers hidden throughout the game. Inside of the Zodiac Chambers, you’ll find a total of nine Zodiac Weapons, and three Zodiac Powers.
Below is the list of Zodiac weapons and powers that you can find, and where to find them.
Aquarius Blade – In Chapter 23, after grinding the first rail, get back on and ride it the way you came and it will take you to the chamber.
Cancer Claws – In Chapter 8, in the Constellation Room, jump up to the first platform and walk counterclockwise all the way around and fall back down behind a group of stars where you’ll find a door leading to a portal to the chamber.
Capricorn Club – In Chapter 20, look for the jail cells in the castle. Inside of the cells you’ll find a switch on the ground which will open another cell. Inside of the cell, you’ll find a hidden passageway to another cell that leads to the chamber.
Gemini Orbitars – In Chapter 6, defeat Dark Pit in the underground temple, then check the corners of the temple for the entrance to the chamber.
Leo Cannon – In Chapter 10, look for the room with the first Guttler. In the next room, follow the left wall to find the chamber.
Sagittarius Bow – In Chapter 2, in the hallway before you meet Magnus, look behind a tapestry there for the entrance to the chamber.
Scorpio Staff – In Chapter 16, once you find the Aether ring, continue through the level and look for a hole in the ground. As you’re falling, keep rotating your view until you see the portal to the chamber.
Taurus Arm – In Chapter 4, look for the room with two swinging blades. Fall into the pit and you will find a glowing hole near a trapped Clubberskull. Fall down the hole and look for the entry to the chamber behind you.
Virgo Palm – In Chapter 12, head to your right to find a hidden elevator after fighting the Nutski. The portal to the chamber is at the bottom.
Aries Armor – In Chapter 18, go left at the Hot Springs area, and you’ll find a door leading to the chamber.
Libra Sponge – In Chapter 14, look for the boss door and turn around to find an electric door. Get close to the door and dodge through it to find the entrance to the chamber.
Pisces Heal – In Chapter 24, once you get off the first elevator, go down the steps instead of up to find the entrance to the chamber.