In Fable 3 for the Xbox 360, you can get an STD by having unprotected sex with villagers (primarily prostitutes). There are condoms in the game that are very cheap, but what happens if you get an STD, can you get rid of it?
Apparently you can’t, it will stick with you forever, even on multiple playthroughs.
Luckily for you though, there isn’t any itching, bumps, redness, puss, etc. There are no in game consequences to contracting an STD. You can act like a 70’s hippie and spread your “free love” all over Albion.
How many STD’s can you collect? Go pokemon style and catch’em all!