There are a few safes in Dishonored, all with hidden clues on how to open them.
If that’s not what you’re after though and you’d rather just cut right to the chase, I’ve compiled a list of safe combinations for your safe cracking enjoyment.
This should be obvious, but the following is a huge spoiler.
Dishonored Safe Combinations
Mission 1 – Dishonored
The safe is located directly past where Corvo gets his gear
Mission 2 – High Overseer Campbell
This safe is inside Dr. Galvani’s residence
This isn’t a safe, but a locked kennel door in the basement of the mansion
This safe is in the Barracks
Mission 03 – House of Pleasure
This safe is inside the Art Dealer’s house
Combination: (randomized) 6-5-6, 6-9-6, 8-7-9, 1-3-8, or 6-7-9
Mission 04 – The Royal Physician
This safe is located in Pratchett’s House
This safe is behind the painting in the wrecked building
Mission 06 – Return to the Tower
This safe is in the private quarters of Lord Regent Hiram Burrows
Mission 07 – The Flooded District
This safe is under water near the start of Central Rudshore
This safe is in the Old Port District’s sewer